Lysozyme in water-acetonitrile mixtures: Preferential solvation at the inner edge of excess hydration

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Preferential Solvation of Fenofibrate in (Ethanol or Acetone) + Water Mixtures at 298.15 K

The aim of this communication was to expand the results of numerical analyses performed by Sun et al. on their experimental solubility of fenofibrate in aqueous mixtures of ethanol and acetone at 298.15 K, in terms of the evaluation of the preferential solvation of this compound by the organic solvents and water in the saturated mixtures based on the inverse Kirkwood-Buff integrals (IKBI). ...

متن کامل

Acetonitrile-protein interactions: amino acid solubility and preferential solvation.

The solubility of amino acids and the preferential solvent interaction of hen-egg lysozyme in acetonitrile (AN)-water mixtures (<60 w/v% AN) were investigated by means of densimetric and refractometric methods at 25 degreesC. The free energy of transfer from water to aqueous AN was negative for most nonpolar side-chains of amino acids and positive for the peptide group, the extent being compara...

متن کامل

Conductance Studies in Acetonitrile-Water Mixtures

The conductance o f N al in acetonitrile-water mixtures was measured at 25.000 ± 0.001 °C for the whole com position range o f the mixed solvent, the salt molarity ranging from 5 • 10“ 5 to 1 • 10-2 . Using the Fuoss-Hsia equation with the Femandez-Prini parameters, the association constants were computed for several values o f the ion-ion distances. The influence o f the mixed solvent composit...

متن کامل

Hydration of the pyrimidine radical cation and stepwise solvation of protonated pyrimidine with water, methanol, and acetonitrile.

Equilibrium thermochemical measurements using an ion mobility drift cell technique have been utilized to investigate the binding energies and entropy changes associated with the stepwise hydration of the biologically significant ions pyrimidine radical cation and protonated pyrimidine. The binding energy of the hydrated pyrimidine radical cation is weaker than that of the proton-bound dimer pyr...

متن کامل

MD Simulation of the Ion Solvation in Methanol-Water Mixtures

Sodium, calcium and magnesium ions are essential for the biological activity of many polyelectrolytes. This activity depends on a condensation of the metal ions. There are several clues, which suggest that interactions between the polyelectrolyte and metal ions depend on a hydration of the ion. This accounts for the great interest in the hydration of metal ions, particularly in the systems cont...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Journal of Chemical Physics

سال: 2017

ISSN: 0021-9606,1089-7690

DOI: 10.1063/1.4984116